This course offers a fairly rigorous coverage of the organic chemistry of the major classes of biomolecules. It introduces the relationships between chemical structure and biological function within living organisms, which provide a foundation for the understanding of intermediary metabolism. The course begins with a review of the structures of cells and organelles, the essentials of biomolecules, the properties of an aqueous environment, and introduces the central concepts of bioenergetics and thermodynamics. It continues with a description of the structures and functions of proteins, carbohydrates, lipids and nucleic acids. In each case structure and composition of these molecules are related to their biological functions. The laboratory introduces a variety of basic techniques commonly used in the isolation, purification, characterization and analysis of proteins, carbohydrates, lipids and nucleic acids, the principle classes of biomolecules. Three hours lecture and four hours laboratory per week. Prerequisite: CHE 208
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